FHIR Osiris Implementation Guide - Local Development build (v2.1.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
Generated Narrative: Observation
Resource Observation "fhir-osiris-annotation-1"
Profile: Variant Annotation
status: final
category: Laboratory (Observation Category Codes#laboratory)
code: Genetic var assess (LOINC#69548-6)
subject: Patient/L304
value: Present (LOINC#LA9633-4)
hasMember:
derivedFrom: Observation/fhir-osiris-example-snp-1
component
code: DNA Change Type (LOINC#48019-4)
value: O15-4 (OSIRIS#O15-4)
component
code: Gene studied ID (LOINC#48018-6)
value: PI3K (#PI3K)
component
code: Prediction software (LOINC#LP91038-7)
value: SIFT (OSIRIS#SIFT)
component
code: Prediction of the variation effect over the protein (LOINC#LP70194-3)
value: 0.35
component
code: Confidence score (LOINC#93044-6)
value: Deleterious
component
code: Cyto loc ID (LOINC#48001-2)
value: exon 2 ()
component
code: Amino acid change (LOINC#48005-3)
value: p.E542K (Human Genome Variation Society nomenclature#p.E542K)
component
code: Amino acid change type (LOINC#48006-1)
value: Missense (LOINC#LA6698-0)
component
code: Struct var HGVS name (LOINC#81290-9)
value: C0439673 (Unified Medical Language System#C0439673)
component
code: DNA change (LOINC#48004-6)
value: c.1624G>A (Human Genome Variation Society nomenclature#c.1624G>A)
component
code: Incidence on the transcript (LOINC#LP232001-0)
value: C0439673 (Unified Medical Language System#C0439673)